Proteomic Biomarkers in Combination with CA125 for Detection of Epithelial Ovarian Cancer using Pre-diagnostic Serum Samples from the Prostate Lung Colon and Ovary (PLCO) Cancer Screening Trial

BACKGROUND: When detected in early stage (I-II), epithelial ovarian cancer 5-year survival is 70–90%, whereas in late stage (III-IV) 5-year survival slips to < 30%. In our previous report, proteomic biomarkers and cancer antigen 125 (CA125) exhibited a sensitivity of 84% at a specificity of 98% f...

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Hauptverfasser: Moore, Lee E., Pfeiffer, Ruth M., Zhang, Zhen, Lu, Karen H., Fung, Eric T., Bast, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385508/
https://ncbi.nlm.nih.gov/pubmed/21717433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26241
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