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Insertions and deletions trigger adaptive walks in Drosophila proteins

Maps that relate all possible genotypes or phenotypes to fitness—fitness landscapes—are central to the evolution of life, but remain poorly known. An insertion or a deletion (indel) of one or several amino acids constitutes a substantial leap of a protein within the space of amino acid sequences, an...

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Autori principali: Leushkin, Evgeny V., Bazykin, Georgii A., Kondrashov, Alexey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385466/
https://ncbi.nlm.nih.gov/pubmed/22456880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2011.2571
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