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Are Nonsense Alleles of Drosophila melanogaster Genes under Any Selection?
A gene which carries a bona fide loss-of-function mutation effectively becomes a functionless pseudogene, free from selective constraint. However, there is a number of molecular mechanisms that may lead to at least a partial preservation of the function of genes carrying even drastic alleles. We per...
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| Publicado no: | Genome Biol Evol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5888714/ https://ncbi.nlm.nih.gov/pubmed/29425311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evy032 |
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