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Change in plasma Aβ peptides and onset of dementia in adults with Down syndrome

OBJECTIVE: To examine changes in levels of plasma amyloid-β (Aβ) peptides, Aβ42 and Aβ40, in relation to onset of Alzheimer disease (AD) in adults with Down syndrome (DS). METHODS: Plasma Aβ42 and Aβ40 were measured at initial examination and at follow-up in a community-based cohort of 225 adults wi...

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Détails bibliographiques
Auteurs principaux: Schupf, N., Zigman, W.B., Tang, M.-X., Pang, D., Mayeux, R., Mehta, P., Silverman, W.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385463/
https://ncbi.nlm.nih.gov/pubmed/21041786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181fb448b
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