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Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine

CD8 T cells are known to deviate CD4 T-cell responses from Th2 toward Th1. Reduction of Th2 cytokines and increased interferon-γ ameliorates allergic airway disease. We have developed a novel approach to the suppression of allergic airway inflammation, by designing a MHC class I-restricted allergen...

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Main Authors: Wells, JW, Choy, K, Lloyd, CM, Noble, A
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385352/
https://ncbi.nlm.nih.gov/pubmed/19079334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2008.69
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