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T-cell receptor retrogenic mice: a rapid, flexible alternative to T-cell receptor transgenic mice
The T-cell receptor (TCR) is unique in its complexity. It determines not only positive (life) and negative (death) selection in the thymus, but also mediates proliferation, anergy, differentiation, cytotoxicity and cytokine production in the periphery. Through its association with six CD3 signalling...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385026/ https://ncbi.nlm.nih.gov/pubmed/22348644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03574.x |
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