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Generation of T Cell Receptor Retrogenic Mice: Improved Retroviral Mediated Stem Cell Gene Transfer
The utilization of retrogenic mice offers a rapid and flexible approach to T-cell receptor transgenic mice. By transducing bone marrow progenitor cells with retrovirus that encodes a given TCR alpha and beta subunit, TCR retrogenic mice can be generated in as little as 4-6 weeks whereas conventional...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832243/ https://ncbi.nlm.nih.gov/pubmed/24008379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2013.111 |
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