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Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

The M2 protein from the influenza A virus, an acid-activated proton-selective channel, has been the subject of numerous conductance, structural, and computational studies. However, little is known at the atomic level about the heart of the functional mechanism for this tetrameric protein, a His(37)-...

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Autors principals: Sharma, Mukesh, Yi, Myunggi, Dong, Hao, Qin, Huajun, Peterson, Emily, Busath, David D., Zhou, Huan-Xiang, Cross, Timothy A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384994/
https://ncbi.nlm.nih.gov/pubmed/20966252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1191750
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