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Conformational heterogeneity of the M2 proton channel and a structural model for channel activation

The M2 protein of influenza virus A is a proton-selective ion channel activated by pH. Structure determination by solid-state and solution NMR and X-ray crystallography has contributed significantly to our understanding, but channel activation may involve conformations not captured by these studies....

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Détails bibliographiques
Auteurs principaux: Yi, Myunggi, Cross, Timothy A., Zhou, Huan-Xiang
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726395/
https://ncbi.nlm.nih.gov/pubmed/19633188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906553106
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