Native and Complexed IGF-1: Biodistribution and Pharmacokinetics in Infantile Neuronal Ceroid Lipofuscinosis

Infantile neuronal ceroid lipofuscinosis (INCL) is a severe neurodegenerative disorder of childhood characterized by selective death of cortical neurons. Insulin-like growth factor 1 (IGF-1) is important in embryonic development and is considered as a potential therapeutic agent for several disorder...

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Detalhes bibliográficos
Main Authors: Huhtala, Tuulia, Rytkönen, Jussi, Jalanko, Anu, Kaasalainen, Martti, Salonen, Jarno, Riikonen, Raili, Närvänen, Ale
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384888/
https://ncbi.nlm.nih.gov/pubmed/22778966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/626417
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