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Mutagenesis and Repair Induced by the DNA Advanced Glycation End Product N(2)-1-(Carboxyethyl)-2′-deoxyguanosine in Human Cells
[Image: see text] Glycation of biopolymers by glucose-derived α-oxo-aldehydes such as methylglyoxal (MG) is believed to play a major role in the complex pathologies associated with diabetes and metabolic disease. In contrast to the extensive literature detailing the formation and physiological conse...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384727/ https://ncbi.nlm.nih.gov/pubmed/21355561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101933p |
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