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Crystal Structure of an Activated Variant of Small Heat Shock Protein Hsp16.5

How does the sequence of a single Small Heat Shock Protein (sHSP) assemble into oligomers of different sizes? To gain insight into the underlying structural mechanism, we determined the crystal structure of an engineered variant of Methanocaldococcus jannaschii Hsp16.5 wherein a 14 amino acid peptid...

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Auteurs principaux: Mchaourab, Hassane S., Lin, Yi-Lun, Spiller, Benjamin W.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384710/
https://ncbi.nlm.nih.gov/pubmed/22670769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300525x
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