Development of AAVLP(HPV16/31L2) Particles as Broadly Protective HPV Vaccine Candidate

The human papillomavirus (HPV) minor capsid protein L2 is a promising candidate for a broadly protective HPV vaccine yet the titers obtained in most experimental systems are rather low. Here we examine the potential of empty AAV2 particles (AAVLPs), assembled from VP3 alone, for display of L2 epitop...

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Autors principals: Nieto, Karen, Weghofer, Margit, Sehr, Peter, Ritter, Mirko, Sedlmeier, Sebastian, Karanam, Balasubramanyam, Seitz, Hanna, Müller, Martin, Kellner, Markus, Hörer, Markus, Michaelis, Uwe, Roden, Richard B. S., Gissmann, Lutz, Kleinschmidt, Jürgen A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384601/
https://ncbi.nlm.nih.gov/pubmed/22761884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039741
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