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Intergenic Polycomb target sites are dynamically marked by non-coding transcription during lineage commitment

Non-coding (nc) RNAs are involved both in recruitment of vertebrate Polycomb (PcG) proteins to chromatin, and in activation of PcG target genes. Here we investigate dynamic changes in the relationship between ncRNA transcription and recruitment of PcG proteins to chromatin during differentiation. Pr...

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Main Authors: Hekimoglu-Balkan, Betül, Aszodi, András, Heinen, Robert, Jaritz, Markus, Ringrose, Leonie
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384584/
https://ncbi.nlm.nih.gov/pubmed/22336714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.19102
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