Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects

BACKGROUND: To get insight into molecular mechanisms underlying insulin resistance, we compared acute in vivo effects of insulin on adipose tissue transcriptional profiles between obese insulin-resistant and lean insulin-sensitive women. METHODS: Subcutaneous adipose tissue biopsies were obtained be...

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Autors principals: Soronen, Jarkko, Laurila, Pirkka-Pekka, Naukkarinen, Jussi, Surakka, Ida, Ripatti, Samuli, Jauhiainen, Matti, Olkkonen, Vesa M, Yki-Järvinen, Hannele
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384471/
https://ncbi.nlm.nih.gov/pubmed/22471940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-9
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