The Clinical Pharmacogenomics Implementation Consortium: CPIC Guideline for SLCO1B1 and Simvastatin-Induced Myopathy

Cholesterol reduction from statin therapy has been one of the greatest public health successes in modern medicine. Simvastatin is among the most commonly used prescription medications. A non-synonymous coding single-nucleotide polymorphism (SNP), rs4149056, in SLCO1B1 markedly increases systemic exp...

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Main Authors: Wilke, RA, Ramsey, LB, Johnson, SG, Maxwell, WD, McLeod, HL, Voora, D, Krauss, RM, Roden, DM, Feng, Q, Cooper-DeHoff, RM, Gong, L, Klein, TE, Wadelius, M, Niemi, M
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Translation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384438/
https://ncbi.nlm.nih.gov/pubmed/22617227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.57
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