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Bacillus subtilis genome editing using ssDNA with short homology regions

In this study, we developed a simple and efficient Bacillus subtilis genome editing method in which targeted gene(s) could be inactivated by single-stranded PCR product(s) flanked by short homology regions and in-frame deletion could be achieved by incubating the transformants at 42°C. In this proce...

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Detalhes bibliográficos
Main Authors: Wang, Yang, Weng, Jun, Waseem, Raza, Yin, Xihou, Zhang, Ruifu, Shen, Qirong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384351/
https://ncbi.nlm.nih.gov/pubmed/22422839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks248
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