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HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing
CD45 encodes a trans-membrane protein-tyrosine phosphatase expressed in diverse cells of the immune system. By combinatorial use of three variable exons 4–6, isoforms are generated that differ in their extracellular domain, thereby modulating phosphatase activity and immune response. Alternative spl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384337/ https://ncbi.nlm.nih.gov/pubmed/22402488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks221 |
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