HnRNP L and L-like cooperate in multiple-exon regulation of CD45 alternative splicing

CD45 encodes a trans-membrane protein-tyrosine phosphatase expressed in diverse cells of the immune system. By combinatorial use of three variable exons 4–6, isoforms are generated that differ in their extracellular domain, thereby modulating phosphatase activity and immune response. Alternative spl...

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Hlavní autoři: Preußner, Marco, Schreiner, Silke, Hung, Lee-Hsueh, Porstner, Martina, Jäck, Hans-Martin, Benes, Vladimir, Rätsch, Gunnar, Bindereif, Albrecht
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384337/
https://ncbi.nlm.nih.gov/pubmed/22402488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks221
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