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CTCF binds to sites in the major histocompatibility complex that are rapidly reconfigured in response to interferon-gamma
Activation of the major histocompatibility complex (MHC) by interferon-gamma (IFN−γ) is a fundamental step in the adaptive immune response to pathogens. Here, we show that reorganization of chromatin loop domains in the MHC is evident within the first 30 min of IFN−γ treatment of fibroblasts, and th...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384298/ https://ncbi.nlm.nih.gov/pubmed/22367884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks158 |
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