Llwytho...

Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1

Histone acetyltransferase 1 is the founding member of the histone acetyltransferase superfamily and catalyzes lysine acetylation of newly synthesized histone H4. Here we report a 1.9-Å resolution crystal structure of human histone acetyltransferase 1 in complex with acetyl coenzyme A and histone H4...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Hong, Moshkina, Natasha, Min, Jinrong, Zeng, Hong, Joshua, Jennifer, Zhou, Ming-Ming, Plotnikov, Alexander N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384170/
https://ncbi.nlm.nih.gov/pubmed/22615379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114117109
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