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Structural basis for substrate specificity and catalysis of human histone acetyltransferase 1
Histone acetyltransferase 1 is the founding member of the histone acetyltransferase superfamily and catalyzes lysine acetylation of newly synthesized histone H4. Here we report a 1.9-Å resolution crystal structure of human histone acetyltransferase 1 in complex with acetyl coenzyme A and histone H4...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384170/ https://ncbi.nlm.nih.gov/pubmed/22615379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114117109 |
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