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Protein kinase Cα and integrin-linked kinase mediate the negative axon guidance effects of Sonic hedgehog

In addition to its role as a morphogen, Sonic hedgehog (Shh) has also been shown to function as a guidance factor that directly acts on the growth cones of various types of axons. However, the noncanonical signaling pathways that mediate the guidance effects of Shh protein remain poorly understood....

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Detalhes bibliográficos
Main Authors: Guo, Daorong, Standley, Clive, Bellve, Karl, Fogarty, Kevin, Bao, Zheng-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383945/
https://ncbi.nlm.nih.gov/pubmed/22521536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.03.008
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