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Sonic Hedgehog Has a Dual Effect on the Growth of Retinal Ganglion Axons Depending on Its Concentration

The stereotypical projection of retinal ganglion cell (RGC) axons to the optic disc has served as a good model system for studying axon guidance. By both in vitro and in vivo experiments, we show that a secreted molecule, Sonic hedgehog (Shh), may play a critical role in the process. It is expressed...

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Detalhes bibliográficos
Main Authors: Kolpak, Adrianne, Zhang, Jinhua, Bao, Zheng-Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564194/
https://ncbi.nlm.nih.gov/pubmed/15800198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4938-04.2005
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