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Prediction of SAMPL3 Host-Guest Affinities with the Binding Energy Distribution Analysis Method (BEDAM)

BEDAM calculations are described to predict the free energies of binding of a series of anaesthetic drugs to a recently characterized acyclic cucurbituril host. The modeling predictions, conducted as part of the SAMPL3 host-guest affinity blind challenge, are generally in good quantitative agreement...

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Bibliografische gegevens
Hoofdauteurs: Gallicchio, Emilio, Levy, Ronald M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383899/
https://ncbi.nlm.nih.gov/pubmed/22354755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-012-9552-3
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