Delayed administration of a small molecule TrkB ligand promotes recovery after hypoxic- ischemic stroke

BACKGROUND AND PURPOSE: Stroke is the leading cause of long-term disability in the United States, yet no drugs are available that are proven to improve recovery. Brain-derived neurotrophic factor (BDNF) stimulates neurogenesis and plasticity, processes that are implicated in stroke recovery. It bind...

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Detalhes bibliográficos
Main Authors: Han, Jullet, Pollak, Julia, Yang, Tao, Siddiqui, Mohammad R., Doyle, Kristian P., Taravosh-Lahn, Kereshmeh, Cekanaviciute, Egle, Han, Alex, Goodman, Jeremy Z., Jones, Britta, Jing, Deqiang, Massa, Stephen M., Longo, Frank M., Buckwalter, Marion S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383889/
https://ncbi.nlm.nih.gov/pubmed/22535263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.641878
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