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Mouse skeletal muscle fiber-type specific macroautophagy and muscle wasting is regulated by a Fyn/STAT3/Vps34 signaling pathway

Skeletal muscle atrophy induced by aging (sarcopenia), inactivity and prolonged fasting states (starvation) is predominantly restricted to glycolytic type II muscle fibers and typical spares oxidative type I fibers. However, the mechanisms accounting for muscle fiber type specificity of atrophy have...

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Detalhes bibliográficos
Main Authors: Yamada, Eijiro, Bastie, Claire C., Koga, Hiroshi, Wang, Yichen, Cuervo, Ana Maria, Pessin, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383827/
https://ncbi.nlm.nih.gov/pubmed/22745922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.03.014
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