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Hfe Deficiency Impairs Pulmonary Neutrophil Recruitment in Response to Inflammation

Regulation of iron homeostasis and the inflammatory response are tightly linked to protect the host from infection. Here we investigate how imbalanced systemic iron homeostasis in a murine disease model of hereditary hemochromatosis (Hfe(−/−) mice) affects the inflammatory responses of the lung. We...

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Autores principales: Benesova, Karolina, Vujić Spasić, Maja, Schaefer, Sebastian M., Stolte, Jens, Baehr-Ivacevic, Tomi, Waldow, Katharina, Zhou, Zhe, Klingmueller, Ursula, Benes, Vladimir, Mall, Marcus A., Muckenthaler, Martina U.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383765/
https://ncbi.nlm.nih.gov/pubmed/22745741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039363
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