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AF1q: A Novel Mediator of Basal and 4-HPR-Induced Apoptosis in Ovarian Cancer Cells

BACKGROUND: Fenretinide (4-HPR) is a synthetic retinoid that exhibits potent antitumor and chemopreventive activities against different malignancies, including ovarian tumors. We previously showed that in ovarian cancer cells, 4-HPR induces apoptosis through a signaling cascade starting from reactiv...

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Huvudupphovsmän: Tiberio, Paola, Cavadini, Elena, Callari, Maurizio, Daidone, Maria Grazia, Appierto, Valentina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383705/
https://ncbi.nlm.nih.gov/pubmed/22761939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039968
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