Sodium 4-Carboxymethoxyimino-(4-HPR) a Novel Water-Soluble Derivative of 4-Oxo-4-HPR Endowed with In Vivo Anticancer Activity on Solid Tumors

4-oxo-N-(4-hydroxyphenyl)retinamide (4-oxo-4-HPR), an active polar metabolite of the synthetic retinoid N-(4-hydroxyphenyl)retinamide (4-HPR), was shown to exert promising antitumor activity through at least two independent mechanisms of action. Specifically, differently from 4-HPR and other retinoi...

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Vydáno v:Front Pharmacol
Hlavní autoři: Tiberio, Paola, Cavadini, Elena, Cleris, Loredana, Dallavalle, Sabrina, Musso, Loana, Daidone, Maria G., Appierto, Valentina
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405676/
https://ncbi.nlm.nih.gov/pubmed/28491037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00226
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