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Vismodegib
Vismodegib (GDC-0449), an orally bioavailable small molecule inhibitor of Hedgehog signaling, was recently approved by the U.S. Food and Drug Administration for the treatment of basal cell carcinoma that is either metastatic or locally advanced in patients who are not candidates for surgical resecti...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383648/ https://ncbi.nlm.nih.gov/pubmed/22653209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3753 |
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