ロード中...
Ebselen and congeners inhibit NADPH-oxidase 2 (Nox2)-dependent superoxide generation by interrupting the binding of regulatory subunits
NADPH-oxidases are a primary source of reactive oxygen species (ROS), which function in normal physiology and, when overproduced, in pathophysiology. Recent studies using mice deficient in Nox2 identify this isoform as a novel target against Nox2-implicated inflammatory diseases. Nox2 activation dep...
保存先:
| 主要な著者: | , , , , , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383625/ https://ncbi.nlm.nih.gov/pubmed/22726689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.04.015 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|