Differential impact of structurally different anti-diabetic drugs on proliferation and chemosensitivity of acute lymphoblastic leukemia cells

Hyperglycemia during hyper-CVAD chemotherapy is associated with poor outcomes of acute lymphoblastic leukemia (ALL) (Cancer 2004; 100:1179–85). The optimal clinical strategy to manage hyperglycemia during hyper-CVAD is unclear. To examine whether anti-diabetic pharmacotherapy can influence chemosens...

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Autors principals: Pan, Jingxuan, Chen, Chun, Jin, Yanli, Fuentes-Mattei, Enrique, Velazquez-Tores, Guermarie, Benito, Juliana Maria, Konopleva, Marina, Andreeff, Michael, Lee, Mong-Hong, Yeung, Sai-Ching Jim
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383592/
https://ncbi.nlm.nih.gov/pubmed/22659796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.20770
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