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Analysis of the psoralen-crosslinking pattern in chromatin DNA by exonuclease digestion.

When chromatin is photoreacted with psoralen, crosslinks occur preferentially in the linker DNA between nucleosomes. The pattern of these crosslinks can be analysed by exonuclease digestion of random DNA fragments, since the exonucleases tested stop at sites of psoralen-crosslinks. Further digestion...

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Bibliografske podrobnosti
Main Authors: Widmer, R M, Koller, T, Sogo, J M
Format: Artigo
Jezik:Inglês
Izdano: 1988
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC338348/
https://ncbi.nlm.nih.gov/pubmed/2841647
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