Structural interconversion of alternating purine-pyrimidine inverted repeats cloned in supercoiled plasmids.
Two self complementary oligonucleotides, T(GC)4AT(GC)4ACATG and C(GC)2(AT)5 (GC)3ATG, were synthesized and cloned into plasmids. Negative supercoiling causes a structural transition in the primary helix of both inserts. The first sequence converts into the left-handed helix, whereas the second seque...
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| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1988
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3405754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.14.6915 |
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