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Regulation of TGF–β signal transduction by mono- and deubiquitylation of Smads
Polyubiquitylation leading to proteasomal degradation is a well-established mechanism for regulating TGF-β signal transduction components such as receptors and Smads. Recently, an equally important role was suggested for monoubiquitylation of both Smad4 and Receptor-associated Smads that regulates t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383349/ https://ncbi.nlm.nih.gov/pubmed/22710170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.03.037 |
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