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Toll-like receptor (TLR) and Inflammasome Actions in the Central Nervous System: New and Emerging Concepts

During the past ten years, much attention has been focused towards elucidating the impact of Toll-like receptors (TLRs) in CNS innate immunity. TLR signaling triggers the transcriptional activation of pro-IL-1β and pro-IL-18 that are processed into their active forms by the inflammasome. Recent stud...

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Autors principals: Hanamsagar, Richa, Hanke, Mark L., Kielian, Tammy
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383346/
https://ncbi.nlm.nih.gov/pubmed/22521509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.03.001
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