Hyperglycemia and Renal Mass Ablation Synergistically Augment Albuminuria in the Diabetic Subtotally Nephrectomized Rat: Implications for Modeling Diabetic Nephropathy

BACKGROUND/AIMSBACKGROUND/AIMS: While experimental models that emulate diabetic nephropathy are valuable tools for elucidating pathogenetic mechanisms and developing novel therapies, existing models imperfectly recapitulate human disease. In diabetes, hyperglycemia and hemodynamic forces act in conc...

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Detalhes bibliográficos
Main Authors: Chen, Li-Hao, Stead, Bailey, Advani, Suzanne L., Yaqoob, Noreen, Thai, Kerri, Kabir, M. Golam, Yuen, Darren A., Connelly, Kim A., Gilbert, Richard E., Advani, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383305/
https://ncbi.nlm.nih.gov/pubmed/22739500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000338272
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