Detecting BRAF Mutations in Formalin-Fixed Melanoma: Experiences with Two State-of-the-Art Techniques

BACKGROUND: Melanoma is characterized by a high frequency of BRAF mutations. It is unknown if the BRAF mutation status has any predictive value for therapeutic approaches such as angiogenesis inhibition. PATIENTS AND METHODS: We used 2 methods to analyze the BRAF mutation status in 52 of 62 melanoma...

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Hauptverfasser: Schoenewolf, Nicola L., Dummer, Reinhard, Mihic-Probst, Daniela, Moch, Holger, Simcock, Mathew, Ochsenbein, Adrian, Gillessen, Silke, Schraml, Peter, von Moos, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: S. Karger AG 2012
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Published online: June, 2012
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383294/
https://ncbi.nlm.nih.gov/pubmed/22740817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000339300
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