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Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast

Sphingolipids are crucial components of membranes, and sphingolipid metabolites serve as signaling molecules. Yeast Orm1 and Orm2 belong to a conserved family of ER membrane proteins that regulate serine palmitoyltransferase, which catalyzes the first and rate-limiting step in sphingolipid synthesis...

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Autors principals: Liu, Ming, Huang, Chunjuan, Polu, Surendranath R., Schneiter, Roger, Chang, Amy
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383258/
https://ncbi.nlm.nih.gov/pubmed/22328531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.100578
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