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Determining Serpin Conformational Distributions with Single Molecule Fluorescence
Conformational plasticity is key to inhibitory serpin function, and this plasticity gives serpins relatively easy access to alternative, dysfunctional conformations. Thus, a given serpin population may contain both functional and dysfunctional proteins. Single molecule fluorescence (SMF), with its a...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383071/ https://ncbi.nlm.nih.gov/pubmed/22078542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-385950-1.00016-X |
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