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structurE of adeno-associated virus-2 In Complex with Neutralizing Monoclonal antibodY A20
The use of adeno-associated virus (AAV) as a gene therapy vector is limited by the host neutralizing immune response. The cryo-electron microscopy (EM) structure at 8.5 Å resolution is determined for a complex of AAV-2 with the Fab′ fragment of monoclonal antibody (MAb) A20, the most extensively cha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383000/ https://ncbi.nlm.nih.gov/pubmed/22682774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.05.004 |
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