TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients

There is strong evidence that both adoptive T cell transfer and T cell checkpoint blockade can lead to regression of human melanoma. However, little data are available on the effect of these cancer therapies on the tumor-reactive T cell compartment. To address this issue we have profiled therapy-ind...

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Detalhes bibliográficos
Main Authors: Kvistborg, Pia, Shu, Chengyi Jenny, Heemskerk, Bianca, Fankhauser, Manuel, Thrue, Charlotte Albæk, Toebes, Mireille, van Rooij, Nienke, Linnemann, Carsten, van Buuren, Marit M., Urbanus, Jos H.M., Beltman, Joost B., thor Straten, Per, Li, Yong F., Robbins, Paul F., Besser, Michal J., Schachter, Jacob, Kenter, Gemma G., Dudley, Mark E., Rosenberg, Steven A., Haanen, John B.A.G., Hadrup, Sine Reker, Schumacher, Ton N.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382882/
https://ncbi.nlm.nih.gov/pubmed/22754759
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