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Fighting cancer by disrupting C-terminal methylation of signaling proteins
Protein methylation at the C-terminus of mammalian isoprenylated proteins has been implicated in membrane attachment, protein-protein interactions, and protein stability. A new paper describes surprising results: in the absence of methylation some target proteins have increased stability, whereas ot...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC338270/ https://ncbi.nlm.nih.gov/pubmed/14966560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421059 |
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