Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4(+) T cells

Glucocorticoids have potent immunosuppressive properties, but their effects are often modulated by the conditions prevailing in the local immune milieu. In this study we determined whether the action of glucocorticoids is influenced by the degree of signaling during T cell activation. We found that...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Tsitoura, Daphne C., Rothman, Paul B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2004
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14966571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI18975
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