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Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4(+) T cells

Glucocorticoids have potent immunosuppressive properties, but their effects are often modulated by the conditions prevailing in the local immune milieu. In this study we determined whether the action of glucocorticoids is influenced by the degree of signaling during T cell activation. We found that...

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Pubblicato in:J Clin Invest
Autori principali: Tsitoura, Daphne C., Rothman, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338260/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14966571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI18975
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