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Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages

Systemic infections with HPAIVs, such as H5N1, are characterized by cytokine burst and sepsis. We investigated the role of human monocyte-derived macrophages in these events after infection with different influenza virus strains. Macrophages were infected with low pathogenic H1N1 (PR8) or high patho...

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Autori principali: Friesenhagen, Judith, Boergeling, Yvonne, Hrincius, Eike, Ludwig, Stephan, Roth, Johannes, Viemann, Dorothee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382316/
https://ncbi.nlm.nih.gov/pubmed/22442495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0911479
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