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Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus)
FX-binding ablated adenovirus type 5 (Ad5) vectors have been genetically engineered to ablate the interaction with coagulation factor X (FX) resulting in substantially reduced hepatocyte transduction following intravenous administration in rodents. Here, we quantify viral genomes and gene transfer m...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382196/ https://ncbi.nlm.nih.gov/pubmed/21677690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.87 |
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