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Clopidogrel: A Case for Indication-Specific Pharmacogenetics
The CYP2C19*2 loss-of-function allele is associated with reduced generation of active metabolites of clopidogrel. However, meta-analyses have supported or discounted the impact of genotype on adverse cardiovascular outcomes during clopidogrel therapy, depending on studies included in the analysis. H...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382015/ https://ncbi.nlm.nih.gov/pubmed/22513313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2012.21 |
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