Analysis of case–control association studies with known risk variants

Motivation: The question of how to best use information from known associated variants when conducting disease association studies has yet to be answered. Some studies compute a marginal P-value for each Several Nucleotide Polymorphisms independently, ignoring previously discovered variants. Other s...

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Detalhes bibliográficos
Main Authors: Zaitlen, Noah, Paşaniuc, Bogdan, Patterson, Nick, Pollack, Samuela, Voight, Benjamin, Groop, Leif, Altshuler, David, Henderson, Brian E., Kolonel, Laurence N., Marchand, Loic Le, Waters, Kevin, Haiman, Christopher A., Stranger, Barbara E., Dermitzakis, Emmanouil T., Kraft, Peter, Price, Alkes L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381970/
https://ncbi.nlm.nih.gov/pubmed/22556366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts259
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