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Neutrophil cerebrovascular transmigration triggers rapid neurotoxicity through release of proteases associated with de-condensed DNA

Cerebrovascular inflammation contributes to diverse central nervous system (CNS) disorders through mechanisms that are incompletely understood. The recruitment of neutrophils to the brain can contribute to neurotoxicity, particularly during acute brain injuries such as cerebral ischaemia, trauma and...

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Detalhes bibliográficos
Main Authors: Allen, Charlotte, Thornton, Peter, Denes, Adam, McColl, Barry W., Pierozynski, Adam, Monestier, Marc, Pinteaux, Emmanuel, Rothwell, Nancy J., Allan, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381844/
https://ncbi.nlm.nih.gov/pubmed/22661091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200409
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